Monday, May 12, 2008

Gene Linked To Alcohol And Cocaine Dependence

ScienceDaily (May 12, 2008) — Previous family-based research had linked a broad region on chromosome 4q with alcohol dependence (AD). A new study has found that nine of the single nucleotide polymorphisms (SNPs) -- DNA sequence variations -- in the 3' region of the tachykinin receptor 3 gene (TACR3), located within chromosome 4q, have a significant association with AD, particularly those with more severe AD, and co-existing cocaine dependence.

"We believe it is important to identify genes contributing to AD for two primary reasons," said Tatiana M. Foroud, director of the division of hereditary genomics at the Indiana University School of Medicine and first author of the study.

"First, better treatments can be developed which would improve the success rate for those wishing to end their AD," she said. "Second, being able to identify those at greater risk for AD at a young age would allow interventions to be initiated earlier, potentially reducing the likelihood that the individual will become AD."

Click here to read entire article at Science Daily.com

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